By Ronald T. Acton
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1975), Federation Proc. 34, 581 (Abstract #2049). ROBERT A . TOBEY et al. , Tobey, R. , Gurley, L. , (1975), Biochem. phys. Res. Commun. Bio- 63, 126-133. Kraemer, P. , Tobey, R. A. (1972). J. Cell Biol. 55, 713-717. Louie, A. , Dixon, G. , (1973), Nature 243, 164-168. Marks, D. , Paik, W. , Borun, T. , (1973), J. Biol. Chem. 248, 5660-5667. , (1963), J. Cell. Comp. Physiol. 62 (Suppl. 1 ) , 123-140. Mitchison, J. , (1971), "The Biology of the Cell Cycle," Cambridge University Press, London.
REFERENCES Bäsch, R. S. and Goldstein, G. (1974). Proc. Nat. Acad. Sei. A. 71, 1474-1478. Boyse, E. A. and Abbott, J. (1975). Federation Proceedings 34, 24-27. Cantor, H. and Boyse, E. A. (1975). J. Exp. Med. 141, 1376-1389. Goldstein, G. (1968). Lancet 2, 119-122. Goldstein, G. (1974). Nature 247, 11^14. Goldstein, G. (1975). Ann. Y. Acad. Sei. 249, 177-183. Goldstein, A. , Zatz, Μ. , Hardy, M. A. and White, DIFFERENTIATION OF Τ CELLS 47 Α. (19721. proc, Nat, Acad. A, 69, 1800. , Boyse, Ε. , Schlesin^ ger, D .
The signal, as in other systems where expression of differ- entiated function is triggered, appears to act through modulation of cyclic AMP levels. There is much evidence that cyclic nucleo- tides, in turn, function by regulating the activity of protein Phosphokinase. , 1976). ) biochemical events, some- times requiring cell division, occur when commitment to differentiation is induced in more pluripotent cells. REFERENCES 1. , Bourne, H. , Insel, P. , Melmon, K. L. and Tomkins G. M. In Recent Progress in Hormone Research CR.