An Introduction to Biochemistry by William Robert Fearon (Auth.)

By William Robert Fearon (Auth.)

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Dublin Soc, 20, 531. FEARON, W. R. " London : Heinemann. Fox, H. , and H . " Proc. Roy. Soc, B, 108, 157. HENDERSON, L. J. " London. KING, E. , and T. H. " Physiol. , 18, 329. LEWIS, H. B. " Physiol. , 4, 394. LOTKA, A. J . " Baltimore. MCCANCE, R. A. " Lancet, 230, 643, 704, 764, 823. MCCANCE, R. A. " Proc. Roy. Soc, B, 814, 245. MCCLURE, F . J. " Physiol. , 13, 277. MARETT, J . R. " London. MINOT, A. S. " Physiol. , 18, 554. ORR, J . , and I. " Med. Res. , 123. OSBORN, H. F . " London. RAMAGE, H.

Under these conditions, iron is nonavailable, and is excreted by the intestine. Iron in the organic form of hsem is not readily released by gastric digestion. McCance found that 15-18 mg. of iron are retained when 50 mg. are given daily as sulphate or chloride to a subject in a state of iron equilibrium, but none is retained when the 50 mg. are given in the form of haem. For this reason, muscle and dried blood are poor sources of nutritional iron. Assimilated iron is not returned to the intestine, which, according to McCance, " has no power of regulating by excretion the amount of iron in the body " (1938).

Only eight elements are present in the earth's crust in concentra­ tions of more than 1 per cent. They are : O, Si, AI, Fe, Ca, Na, K and Mg, and together make up 98 per cent, of the surface. About 1-1 per cent, is made up of Ti, P, Ca and H (as H 2 0). The remaining 80 elements together constitute only 0-5 per cent, of the crust. BIOLOGICAL ELEMENTS 43 A 70 kg. human body contains approximately : oxygen, 46 kg. ; carbon, 12 kg. ; hydrogen, 7-2 kg. ; nitrogen, 1-7 kg. ; calcium, 1-1 kg. ; phosphorus, 630 gm.

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